Medical research aka clinical research perform tests and procedures in the laboratory. Development of a drug or treatment is created, and eventually tests are done with animals. Shall we explore the 10 Experimental Medical treatment discoveries?
Once they are at a stage where there are no side effects or fatalities then choosing to move with the most promising experimental treatments into ‘clinical trials’ are planned. These are steps that are all conducted in ‘phases’, starting with research of molecules or elements, development of a drug then testing on animals.
Once testing is found safe with no harmful side effects, it then moves into the first phase with a small group of qualified people. Qualified people refers to those with specific health issues.
Begin with a Call – Out
The health team will continue delivering health care services, and the new treatments or tests ordered by the, or a team of Doctor(s) to measure and evaluate the outcome with help from qualified patients.
The team must first seek government ‘approval‘ to dispense the medications, and/or procedures. Volunteer patients safety is a mandatory priority.
A call-out for volunteers is made, usually for the latest promising medical drug or treatments. Would you volunteer or be willing to join a clinical trial with pay?
the 10 Experimental Medical Treatment Discoveries
Canadian study discovers way to make ‘universal’ organs for all transplant recipients, 2022
A new first-of-its-kind study out of Canada has discovered a way to make “universal” organs that could be used in all transplant recipients regardless of their blood type. The proof-of-concept study has demonstrated the possibility of safely converting blood type in donor organs for transplantation, which would make the wait shorter for patients, but also decrease mortality. Read more.
Experimental treatment helps patients hospitalized with COPD, 2021
People with chronic obstructive pulmonary disease (COPD) can no longer take in all the air they need. A research team investigated the use of hyaluronan a long-chain sugar that’s naturally secreted by many tissues, including within the lungs. Read more.
This experimental drug could change the field of cancer research,2022
A tiny group of people just experienced something of a scientific miracle: their cancer simply vanished after an experimental treatment.The trial resulted in every single one of their tumors disappearing. Read more.
Experimental Brain Cancer Treatment Is a Success, 2016
Using the immune system to beat cancer is quickly becoming a promising new strategy for battling tumors. A report published in the New England Journal of Medicine say that the same immuneotherapy that is successful against blood cancers also helped a patient with advanced brain cancer. Read more.
How an experimental treatment beat a little girl’s cancer,2022
The first child ever to receive genetically-modified T cells. The experimental treatment cured her leukemia, and the success of her case has allowed all kinds of cellular therapies to be developed. Read more.
Experimental approach to treating pancreatic cancer heralded as a success,2022
A new gene therapy shrank the tumors of a woman with pancreatic cancer. Researchers think it has the potential to benefit millions more people. Read more.
Nasal cartilage relieves osteoarthritis in the knee, 2021
Cartilage cells from the nasal septum can help repair cartilage injuries in the knee — they can also withstand the chronic inflammatory tissue environment in osteoarthritis and even counteract the inflammation. Read more.
Electrical zaps can ‘reawaken’ lost neural connections, helping paralyzed people walk again, 2022
Scientists identified specific spinal nerve cells that people likely need to regain the ability to walk after paralyzing injuries. Read more.
Ebola vaccines in African countries successfully produced antibodies in kids and adults, 2022
The results of two randomized, placebo-controlled trials analyzing three Ebola vaccine administration strategies show promising results. Read more.
In a 1st, baby’s heart defect successfully treated with injected stem cells, 2022
A baby underwent heart surgeries for a heart defect, and was the first child on record to receive a stem cell injection to patch his heart after surgery. Read more.
End Phase of the Trial
Clinical trials are carried out in two groups, and four phases. Think of it as going from small to large numbers of people.
If the outcomes, evaluations and follow-up evaluations are positive, the new drug or treatment is nationally accepted then there is no further testing needed. The trials are closed.
A new medication is government approved for public dispensing. Paid volunteers are an important factor to the success of this new drug or treatment. I’m grateful for their courage in taking the trial to give us new medical discoveries.
Learn to Explore your Interest
To start your own journey into entering a Cinical trial you can ask your doctor, or he may even ask if you’d be interested. Adults and children may qualify but it’s important to learn as much as possible about the trial.
Some clinical trials will Pay, and others may not. Do not be shy to ASK questions. The main goal is to test, and evaluate the outcomes of new medical treatments or medications.
I think the USA offers payment for clinical trials, and some may offer payment in Canada too. Again, don’t be shy to ask. It’s ok. No animals will be harmed. 🙂
I hope you found this article informative and gained some new insight. Please feel free to leave your Comments, and Share your new found knowledge with others. Use the ‘Ask A Question’ form to make a request on a topic of your own interest. It is FREE to subscribe to my RSS feed.
AIC| An Informal Cornr, all rights reserved. Ginsense writes articles on business skills, development, health, science, technology and society and enjoys advocating for independence, security and a better world for all of us.
Emergency treatment by qualified medical professionals begins once a Good Samaritan calls for help, and the ambulance arrives. The whole medical team has a short window of a few hours to help a victim recover, and survive when a loved one is in one of 7 types of shock.
Shock occurs when the body goes into circulatory failure from damage, and inability to control, or loss from, circulating fluid throughout the body. A dangerous level reached in the reduction of blood flow and delivery of oxygen, to tissues and organs left untreated can lead to collapse, coma, and death.
Tests, blood and lab results and medical alert bracelet or card plus access to their primary doctors’ file on victim is needed to verify the health conditions, and any other underlying health issues before a treatment regimen can begin. Not all victims are so lucky, and do die.
Shock is applied as a ‘catch-all’ phrase since it does not fully define any one set of symptoms. There are seven types of shock and each have differing symptoms but do have a common ‘classic‘ symptom.
7 Types of Shock
Medical research has been able to identify and list the different types of circulatory shock, as follows;
Low volume shock – aka hypovolemic or hemorrhagic shock and occurs when there is low blood flow to skin and muscles from a severe loss of blood, fluid or plasma, and doesn’t fill the circulatory system.
Causes– open wounds to the body and internal organs, loss of plasma from burns, fluid loss from gastroenteritis, vomiting
Symptoms – dramatic blood pressure drop, weakness, confusion, pallor, sweating as the body tries to compensate
Treatment – saline solution and plasma help replace fluids lost, severe blood loss may require a blood transfusion, close any open wounds with sutures, tests such as a CT scan will find any internal bleeding, bleeding in the skull may cause compression of the brain, a hole will need to be drilled to relieve pressure, clamps are used for bleeding from small blood vessels until able to tie them off or use of diathermy, a high frequency electric current.
Neurogenic shock – usually caused by psychological factors and overwhelms the normal bodily functions of the nervous system.
Causes – great trauma, pain, fright, war, crime
Symptoms – low blood pressure, dizziness, nausea, vomiting, catatonic (blank stare), fainting, increased sweating, anxiety, pale skin, and severe shock will show, difficulty breathing, chest pain, weakness, slow heart rhythm (bradycardia), weak pulse, bluish hue skin color or discolored lips and fingers aka cyanosis, hypothermia, will shiver and feel cold
Treatment – raising the feet above the level of the head is usually enough to relieve this type of shock
Septic shock – due to a bacterial infection since some organisms multiply in the bloodstream and release toxins which reacts with blood vessels.
Causes – injury site becomes infected and spreads into the bloodstream.
Symptoms – high fever, chills, rapid breathing, headache, low to high levels delirium, possible skin rash, yellowish hue to the skin, warm hands. Large amounts of infection in the blood leads to septic shock.
Treatment – several treatment strategies are used such as balanced corticosteroid usage, antiendotoxin treatment, vasoactive agents (levosimendan), hyperbaric oxygen treatment, fibrates, and several antioxidant supplements
storage of blood components for medical emergencies
Allergic shock – aka anaphylactic shock (anaphylaxis) is a severe reaction and high sensitivity to an injected foreign protein that directly affects blood vessels and other body tissues.
Causes – insect venom, injection of antibiotic or other medication and/or food.
Symptoms – itchy raised rash, swollen (constricted) airways (bronchospasm), abdominal pain, swollen tongue or throat, and diarrhea.
Treatment – Epipen uses single epinephrine dose, severe shock requires oxygen therapy; intubation to help with breathing, medications via IV line fed, to ; reduce respiratory swelling, antihistamines, narrow blood vessels and raise blood pressure if dangerously low, help block allergic reactions and reduce swelling, low blood pressure
Cardiogenic shock – conditions or events that cause the heart to a decrease in cardiac output (weakened pumping and, or irregular rhythmic action).
Causes – heart attack, inflammation aka myocarditis, severe heart failure, or interference to heart electrical rhythm, pulmonary embolism blocking blood flow to the heart, inflammation of abdominal cavity aka peritonitis, some types of poisoning, spinal injury, street drugs.
Symptoms – rapid breathing, severe shortness of breath, sudden rapid heartbeat (tachycardia), loss of consciousness, weak pulse, low blood pressure (hypotension), cool moist skin, decreasing alertness, low to no urinating at all
Treatment – treatment will focus on reducing damage from lack of oxygen to your heart muscle and other organs, oxygen therapy, IV line will feed fluids and plasma plus medications to reduce ; blood clots, low blood pressure (hypotension), improve pumping function of heart, prevent blood clots and help blood flow, and to prevent formation of blood clots. Surgery may be needed as next step.
Toxic Shock Syndrome, TSS – caused by toxins released by an overgrowth of the bacterium staphylococcus aureus, Streptococcus pyogenes, or Clostridium sordellii within the body.
Causes – affects menstruating women, sometimes men. It’s due to infection and overgrowth of staphylococcus aureus, Streptococcus pyogenes, or Clostridium sordellii bacteria on tampons, internal birth control devices, miscarriage, surgical wounds, abortion, or an open wound. It can recur.
Symptoms – a sudden high fever, low blood pressure, vomiting or diarrhea, a rash that looks like sunburn and sheds in sheets, particularly on your palms and soles, confusion, muscle aches, redness of eyes, mouth and throat, possible seizures, and headaches
Treatment – IV line fed antibiotics, fluids and/or blood transfusion, heart medications for very low blood pressure, dialysis may be required in people if there is kidney failure, supplemental or mechanical oxygen, deep surgical cleaning of an infected wound
Insulin Shock – aka as #Diabetic shock, occurs when the blood sugar levels dip too low and there’s too much insulin.
Causes – skip a meal, changing schedule of taking your insulin, changing amount or timing of meals, increasing physical activity, drinking alcohol on an empty stomach
Symptoms – anxiety, irritability, headache, extreme hunger, dizziness, physical shaking of extremities, pale skin, excessive sweating, slurred speech, confusion, rapid pulse, coordination issues, seizures, fainting, coma plus additional symptoms of nightmares, calling out while sleeping, aggressive behaviour, sweat-soaked clothing or bedding
Treatment – a conscious victim can take a fast-action sugar candy or drink, an unconscious victim may have a Glucogon Injection (similar to Epipen but delivers a sugar), rub sugar on their gums if unconscious, never ‘feed’ an unconscious victim, Paramedics can also give the Glucogon injection, set up IV site, and CPR if necessary. The Hospital will feed sugar intravenously, and victim should wake in 15 minutes. Cardiac arrest can occur and the victim will slip into a coma, organs begin to shut down, once the brain shuts down, death ensues. It’s important to wear a medical bracelet with such health conditions.
time is limited for medical emergencies like shock
Classic Symptoms of Shock
The symptoms for shock will vary and depend on the type of shock that’s been activated. The human body will have it’s own defense mechanisms that automatically respond to the injury. The classic symptoms of shock are as follows;
cold, moist, pale skin especially at the extremities
lips and fingers will be pale
rapid and weak pulse
low blood pressure
low level of consciousness
thirst
low urine output (oliguria)
Emergency treatment can begin with First Aid from a Good Samaritan and then continue in the ambulance by #Paramedics to the hospital. They will act quickly to support the body’s own mechanisms to reduce the severity of shock and lessen the effects of the injury.
medical team work together for #recovery
Treatment
A medical Emergency begins with you or somebody trained with basic First Aid skills, for CPR until the Paramedics from the ambulance arrive, and they will begin the management of shock with overall goals to stop blood loss, increase blood flow to tissues and organs, maintain body heat, oxygen therapy for the heart, relieve pain, splinting wounds or positioning.
It is at this point that medical team members will provide comfort and reassurance to the victim, as this helps support the body’s energy focused on it’s own natural defense mechanisms. Nursing interventions include care for mental health of patients. Covering the victim with a blanket helps keep the body’s normal temperature and circulation. Careful observation will ensure heating the victim does not induce sweating, as this is loss of fluids.
The victim is normally laid flat on his back but if blood loss from wounds occurred they will be positioned on their side to prevent choking or breathing vomitus into their lungs. Care will include setting an IV site for either a blood transfusion, saline, or other blood components (such as plasma), and/or medication therapy, to restore the circulating blood volume.
An oxygen nose cannula or mask will be given to prevent possible onset of respiratory collapse, and possibly a narcotic medication for pain management. This will depend on the type of shock, and Physician orders.
When you may need to Call for Emergency Help
People of all walks of life, ages and income ride a bike, take strolls, and drive around various areas of their neighborhood. We don’t always pay attention to those areas that are not regularly used by the public. They may be closed to the public or just a scarey alley for business use but those most marginalized people will know about those areas.
It is these areas where somebody may need medical emergency help. Next time you walk by a staircase that leads to, who knows where other than to maybe a railroad line, take a quick look up the stairs. Somebody could be laying there trying to call for help.
Some people walk on by without thinking about homeless people whether they be adults or youths. Their thoughts are usually that, ‘oh, they know what to do,’ but NO they don’t always know or may not be ABLE to speak to call for help. This is also the same for our Elderly people, they may not know, have poor hearing nor be able to speak either. Just take five minutes, check.
good neighbors will call for Help
Signs of Distress for Help
Signs of medical distress to ones body does create obvious signs and symptoms. We just have to be observant enough to recognize somebody needs medical help. Did you know? deaths of the Homeless people were never counted? Nobody knows the exact numbers of those that passed away, alone.
The following are signs and symptoms that should get immediate calls for help and to call 911;
breathing problems (difficulty breathing, shortness of breath)
near drowning
deep or large wound
poor self-bandaging with non-medical alternative
sudden ; pain, dizziness, weakness, change of vision, suspect poisonous substance, abdominal pain or when applying light pressure
fresh, continuous bleeding
change in mental status (such as unusual behavior, confusion, difficulty rousing)
chest pain
choking
coughing up or vomiting blood
fainting or unconsciousness
feeling suicidal or talking about committing murder
head or spine injury
severe or persistent vomiting
vehicle accident
burns or smoke inhalation
I don’t think any of us would want some sort of medical episode like, a stroke which could cause dizziness, and then we fall and roll into a nearby ditch and unable to move due to paralysis, unable to speak or move, and having to watch people glance then quickly look away, and ignore you, right?
Unseen Homeless need Help too
requesting help from strangers
A report done by the Canadian Observatory on Homelessness at their Homeless Hub website, states the following;
Several years ago, an information graphic put together by Scott Sørli contrasted the decline in social assistance rates after the Common Sense Revolution (under Conservative Premier Mike Harris) with the increase in homeless deaths in Toronto.
AUTHOR: Gulliver, Tanya (2014) Homeless Hub
The program has since been changed and annual reports are now provided to government and partner organizations that help the homeless. That infographic is heartbreaking and unimaginably inhuman. Ignoring the high rates of deaths of the homeless is NOT a badge of honor for anybody to wear especially our government nor our community.
Answer the Requests for Help
Let’s be that Good Samaritan should the moment arise, and somebody needs your help. Call 911 and get Emergency medical help, quick! Somebody’s life may depend on you. I hope such an event does not happen but we never know, and at least we can do that one easy task.
Fear of the unknown makes people hesitate and maybe stop outright. If this is a concern of yours or somebody you know there are CPR training courses available. A little research online will show who offers the course, pricing, and all other frequently asked questions (FAQ). They will teach you the basic first aid skills that once learned, you know for life even if you’re required to ‘renew’ your Certification.
Let’s remember that not everybody is born with perfect health, so let’s work together to keep our eyes open to those who are vulnerable. I’m sure God would smile. 🙂
I hope you found this article informative and gained some new insight. Please feel free to leave your comments and share your new found knowledge with others. Use the ‘Ask A Question’ form to make a request on a topic of your own interest. It is FREE to subscribe to my RSS feed.
AIC| An Informal Cornr, all rights reserved. Ginsense writes articles at AIC|An Informal Cornr about business skills and development, health, science, technology, society and enjoys advocating for independence, security and a better world for all of us. Learn something new 🙂 Visit today!
Parenting a family whether as a couple or a single parent can be a mix of wonderful then suddenly we get attitude, and we ask our self, ‘who is this person and where is my sweet child?’ We tend to forget our child(ren) are growing into an adult. A few different parenting challenges do arise for us and our children but some behaviors are quite normal.
It’s going to depend on our responses to how we handle this stage of their growth that will be revealed in their adulthood. It’s this next step of their growth that can be a challenge and sets them up towards the adult they will become, or not.
family bonds when done together
The following articles are about different areas and ages where our parenting skills can get challenged, and how we respond sets foundations towards our duty of presenting a healthy adult to society. It’s always good to keep our parenting journey a learning environment for us, and our children.
Read about how parents can open discussions with teaching their child(ren) the importance of staying informed and an engaged citizen for a thriving and peaceful democracy.
It’s common knowledge that the tween and teenage years can be hard on the parent-child relationship. Experiencing defiance, rejection, and ridicule from one’s child is very upsetting for parents.
Is your teenager violent, depressed, abusing alcohol or drugs, or facing other problems? Here’s how to ease the stress at home and help your teen transition into a happy, successful adult.
let unconditional love help us through life storms
Recent work in child development and neuroscience increasingly suggests that children require safe, stable, nurturing relationships and environments to thrive. Evidence shows that stress and trauma, especially when prolonged, can interrupt healthy child development, putting them at risk for lifelong health issues.
Narcissistic Parents or caregivers who display rejecting behavior toward a child will often [purposefully or unconsciously] let a child know, in a variety of ways, that he or she is unwanted.
Not all parenting duties are easy nor are parents picture perfect. Some days we are hard on ourselves, and others behave because of past ‘ghosts’ that haunt them. There is no shame in talking with qualified therapists for yourself, or for your child(ren) to help understand and answer that question, why?
past ghost memories can affect us today
Qualified therapists and counselors are there to help us by listening then help us learn new coping skills, become our better selves, in complete confidentiality. Each day is a new day to press that re-start button, and to make positive changes. Life may not be easy but it can be managed with a healthy outlook.
I hope you found this article informative and gained some new insight. Please feel free to leave your comments and Share your new found knowledge with others. Use the ‘Ask A Question’ form to make a request on a topic of your own interest. It is FREE to subscribe to my RSS feed.
AIC| An Informal Cornr, all rights reserved. Ginsense writes articles on business skills, development, health, science, technology and society and enjoys advocating for independence, security and a better world for all of us.
